NVIDIA RTX 4060 Ti 16GB vs NVIDIA RTX 4080
Side-by-side local AI comparison — VRAM, memory bandwidth, model compatibility, and estimated tokens per second across 70 open-weight models.
Quick verdict
NVIDIA RTX 4080 wins for local AI inference. It has 149% more memory bandwidth, runs 41 models natively (vs 41), and exclusively fits 0 models the other cannot.
Specs comparison
| Spec | NVIDIA RTX 4060 Ti 16GB | NVIDIA RTX 4080 |
|---|---|---|
| VRAM | 16 GB | 16 GB |
| Memory type | GDDR6 | GDDR6X |
| Bandwidth | 288 GB/s | 717 GB/s(+149%) |
| Architecture | Ada Lovelace | Ada Lovelace |
| Backend | CUDA | CUDA |
| Tier | Consumer | Consumer |
| Released | 2023 | 2022 |
| Models (native) | 41 | 41 |
Estimated tokens per second
Computed from memory bandwidth and model active-parameter weight. Assumes model fits natively in VRAM.
| Model | NVIDIA RTX 4060 Ti 16GB | NVIDIA RTX 4080 | Delta |
|---|---|---|---|
| Llama 3.3 70B Instruct(70B) | — | — | — |
| Qwen 3.6 27B(27B) | 26.7 t/s(Q3_K_M) | 66.4 t/s(Q3_K_M) | -60% |
| Llama 3.1 8B Instruct(8B) | 36 t/s(Q8) | 89.6 t/s(Q8) | -60% |
| Qwen 2.5 7B Instruct(7.6B) | 37.9 t/s(Q8) | 94.3 t/s(Q8) | -60% |
Delta is NVIDIA RTX 4060 Ti 16GB relative to NVIDIA RTX 4080.
Only NVIDIA RTX 4060 Ti 16GB can run(0)
No exclusive models — NVIDIA RTX 4080 can run everything NVIDIA RTX 4060 Ti 16GB can.
Only NVIDIA RTX 4080 can run(0)
No exclusive models — NVIDIA RTX 4060 Ti 16GB can run everything NVIDIA RTX 4080 can.
Both run natively(41)
These models fit in VRAM on both GPUs. Bandwidth determines which runs them faster.
- Qwen 3.5 35B-A3B (MoE)352 t/svs876.3 t/s
- Qwen 3.6 35B27.4 t/svs68.3 t/s
- Yi 1.5 34B Chat27.9 t/svs69.5 t/s
- Qwen3 32B29.3 t/svs72.9 t/s
- Qwen 2.5 32B Instruct29.5 t/svs73.5 t/s
- Qwen 2.5 Coder 32B Instruct29.5 t/svs73.5 t/s
- DeepSeek R1 Distill Qwen 32B29.5 t/svs73.5 t/s
- Nemotron 3 Nano 30B264 t/svs657.2 t/s
- Gemma 4 31B31 t/svs77.1 t/s
- Qwen3 30B-A3B (MoE)264 t/svs657.2 t/s
- Gemma 2 27B Instruct35.3 t/svs87.9 t/s
- Gemma 3 27B Instruct26.7 t/svs66.4 t/s
- Qwen 3.6 27B26.7 t/svs66.4 t/s
- Gemma 4 26B (MoE)208.4 t/svs518.9 t/s
- Mistral Small 3.1 24B Instruct24 t/svs59.8 t/s
- Mistral Small 22B25.9 t/svs64.6 t/s
- +25 more on both
Which should you choose?
Choose NVIDIA RTX 4060 Ti 16GB if:
- • You want the newer architecture and longer driver support lifecycle
Choose NVIDIA RTX 4080 if:
- • Faster token generation is the priority
Frequently asked questions
- Which is better for local AI, the NVIDIA RTX 4060 Ti 16GB or NVIDIA RTX 4080?
- For local AI inference, the NVIDIA RTX 4080 has the edge. It offers 16 GB VRAM (vs 16 GB) and 717 GB/s bandwidth (vs 288 GB/s), letting it run 41 models natively in VRAM vs 41 for its rival.
- How much VRAM does the NVIDIA RTX 4060 Ti 16GB have vs the NVIDIA RTX 4080?
- The NVIDIA RTX 4060 Ti 16GB has 16 GB of GDDR6 at 288 GB/s. The NVIDIA RTX 4080 has 16 GB of GDDR6X at 717 GB/s. Both GPUs have the same VRAM amount; bandwidth determines which generates tokens faster.
- Can the NVIDIA RTX 4060 Ti 16GB run Llama 3.3 70B?
- The NVIDIA RTX 4060 Ti 16GB can run Llama 3.3 70B with CPU offload at Q3_K_M, but at reduced speed.
- Can the NVIDIA RTX 4080 run Llama 3.3 70B?
- The NVIDIA RTX 4080 can run Llama 3.3 70B with CPU offload at Q3_K_M, but at reduced speed.
- What is the difference between the NVIDIA RTX 4060 Ti 16GB and NVIDIA RTX 4080 for AI?
- The key difference for AI inference is VRAM and memory bandwidth. The NVIDIA RTX 4060 Ti 16GB has 16 GB VRAM at 288 GB/s (CUDA backend). The NVIDIA RTX 4080 has 16 GB VRAM at 717 GB/s (CUDA backend). VRAM determines which models fit; bandwidth determines tokens per second. The NVIDIA RTX 4060 Ti 16GB runs 41 models natively vs 41 for the NVIDIA RTX 4080.